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Jo & Alex on ‘Grey’s Anatomy’
Jennifer Clasen/Disney General Entertainment Content/Getty

First season original Alex Karev (Justin Chambers) and ninth season newcomer Jo Wilson (Camilla Luddington) begin their flirtation during her first year at the hospital, him in his first attending year and her a fresh faced intern. They get together in season 10, though like mostGrey’sromances, the two endure a bumpy relationship timeline featuring breakups, multiple proposals and even two marriage ceremonies.
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Pacey & Joey on ‘Dawson’s Creek’
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The actor behind Pacey himself took the couple’s grim outlook especially hard. Speaking toEntertainment Weekly in May 2022,Jackson opened upabout his campaign forDawson’s Creekcreator Kevin Williamson to have Pacey and Joey end up together after all.
“I had a whole conversation with Kevin about this,” said the actor, nearly two decades after the show wrapped. “Like, ‘Look, I get it. This is the idea that you had in your head, but I’m just gonna ask you to watch the tale of the tape and this is the more interesting end for these characters.'”
In the end, Jackson got his way – the finale season ends with Pacey and Joey together, living in New York.
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Alexis & Ted on ‘Schitt’s Creek’

From the moment the Rose family moved to Schitt’s Creek, Annie Murphy and Dustin Milligan’s characters, Alexis Rose and Ted Mullens, shared some major chemistry. The town veterinarian even winds up proposing to the former heiress, which she rejects, though they do reunite as a couple and remain steady in the fifth season.
Their relationship begins to fray when Ted departs for a professional opportunity on the Galápagos Islands. After a failed attempt at long distance, their romance meets its demise on amicable terms, as Ted encourages Alexis to pursue her career dreams closer to home while he follows his abroad.
That said, Alexis and Ted’s partnership wasn’t always meant to end. In conversation with Entertainment Weekly,Schitt’s Creekco-creator Dan Levy shared that his character’s wedding was meant to bea double ceremonyshared with Alexis and Ted. Murphy was so pleased with this ending that when it fell through, she “was furious” and “threatened to quit the show.”
But Levy maintained his reasons for cutting off his on-screen sister’s relationship. “Alexis needed to come out of this show liberated in a way that wasn’t necessarily attached to a guy,” he said. “I felt like it would be more fulfilling to that character to have loved and lost and been set on a track that is leading her into her future rather than settle with someone at the end of the show.”
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Ted & Victoria on ‘How I Met Your Mother’
CLIFF LIPSON/CBS

05of 08Connell & Marianne on ‘Normal People’Normal People.Enda Bowe/HuluInNormal People, Paul Mescal and Daisy Edgar-Jones’ characters spend some of their most formative, pivotal years together as they finish up secondary school in Ireland and begin university at Trinity College. The two endure seemingly endless obstacles during their relationship, between family issues, ex-romances and their differing life goals. However, towards the end of the miniseries, Connell and Marianne seem like they’ve finally got the timing right.Then Connell gets accepted to an MFA program in New York, though he’s hesitant to move and risk his future with Marianne. The final episode ends with their solemn decision to separate, with Marianne encouraging Connell to go abroad and pursue a higher degree in writing.
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Connell & Marianne on ‘Normal People’
Normal People.Enda Bowe/Hulu

InNormal People, Paul Mescal and Daisy Edgar-Jones’ characters spend some of their most formative, pivotal years together as they finish up secondary school in Ireland and begin university at Trinity College. The two endure seemingly endless obstacles during their relationship, between family issues, ex-romances and their differing life goals. However, towards the end of the miniseries, Connell and Marianne seem like they’ve finally got the timing right.
Then Connell gets accepted to an MFA program in New York, though he’s hesitant to move and risk his future with Marianne. The final episode ends with their solemn decision to separate, with Marianne encouraging Connell to go abroad and pursue a higher degree in writing.
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Fleabag & Hot Priest on ‘Fleabag '
Amazon Studios

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Jess & Rory on ‘Gilmore Girls’
Milo Ventimiglia and Alexis Bledel in Gilmore Girls.Warner Bros./Everett

Things start to go south for Jess Mariano (Milo Ventimiglia) and Rory Gilmore (Alexis Bledel) towards the end of their senior year, as the couple deal with Rory’s jealous ex, Dean (Jared Padalecki), trying to break them apart. Jess is also secretive, withholding crucial information about his future: He’s not only failing high school; his very presence in Stars Hollow is crucially at stake. What Rory doesn’t know is that Jess’s uncle, Luke, will only permit him to stay in town if he can graduate.
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Ron Batzdorff/NBCU Photo Bank/NBCUniversal via Getty

source: people.com